Article
Examination of Hardy-Weinberg equilibrium in papers of Kidney International: an underused tool.
Kidney international - 1 May 2004
Kocsis István, Györffy Balázs, Németh Eva, Vásárhelyi Barna
Abstract excerpt
BACKGROUND: Population-genetic studies investigating genetic polymorphisms of Mendelian inheritance should always test whether the measured genotype frequencies deviate from the expected one. For this purpose Hardy-Weinberg (HW) criteria are generally used. If genotype distribution of control population misses HW equilibrium, the results should be treated cautiously because the observed genotype distribution in...
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