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Article

[Statistical analysis of genetic polymorphisms in epidemiological studies].

Gaceta sanitaria - 1 Jan 2000

Iniesta Raquel, Guinó Elisabet, Moreno Víctor

Abstract excerpt

Analysis of genetic polymorphisms allows the genes that confer susceptibility to diseases to be analyzed. This paper presents the nomenclature used in genetic epidemiology literature and a basic strategy for statistical analysis of epidemiological studies that use genetic markers. First, a descriptive analysis of a single nucleotide polymorphism is presented, with assessment of Hardy-Weinberg equilibrium. Next,...

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PMID: 16050971
DOI: 10.1157/13078029

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