Article
Drug resistance testing in PBMCs of HIV infected patients.
The new microbiologica - 1 Oct 2001
Tagliaferro L, Menegazzi P, Cataldini S, De Simone M, Chiriacò P, Varnier O E
Abstract excerpt
HIV infected patients are considered a sort of reservoir having different genetically distinct viral variants (quasispecies), that evolve from the starting virus inoculum. Frequently, during replication, HIV can generate nucleotide differences in the new viral population; such genetic changes may be uninfluential in viral "fitness" (replication capacity) or give the virus some advantages under a selective...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.