Article
Error-prone DNA repair and translesion DNA synthesis. II: The inducible SOS hypothesis.
DNA repair - 8 Jun 2005
Bridges Bryn A
Abstract excerpt
Evelyn Witkin hypothesized in 1967 that bacterial cell division is controlled by a repressor which, like the lambda repressor, is inactivated by a complex process that starts with the presence of replication-blocking lesions in the DNA. She further suggested that this might not be the only cellular function to show induction by DNA damage. Three years later, Miroslav Radman, in a privately circulated note,...
Topics
- DNA Repair
- DNA Replication
- DNA, Bacterial
- Dose-Response Relationship, Radiation
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Mutation
- SOS Response, Genetics
- Ultraviolet Rays
