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Article

Does CD95 have tumor promoting activities?

Biochimica et biophysica acta - 25 May 2005

Peter Marcus E, Legembre Patrick, Barnhart Bryan C

Abstract excerpt

CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95. Changes in the expression of CD95 and/or its ligand CD95L are frequently found in human cancer. The downregulation or mutation of CD95 has been proposed as a mechanism by which cancer cells avoid destruction by the immune system through...

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Identifiers

PMID: 15907590
DOI: 10.1016/j.bbcan.2005.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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