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Article

Ephrin signalling controls brain size by regulating apoptosis of neural progenitors.

Nature - 30 Jun 2005

Depaepe Vanessa, Suarez-Gonzalez Nathalie, Dufour Audrey, Passante Lara, Gorski Jessica A, Jones Kevin R, Ledent Catherine, Vanderhaeghen Pierre

Abstract excerpt

Mechanisms controlling brain size include the regulation of neural progenitor cell proliferation, differentiation, survival and migration. Here we show that ephrin-A/EphA receptor signalling plays a key role in controlling the size of the mouse cerebral cortex by regulating cortical progenitor ce...

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PMID: 15902206
DOI: 10.1038/nature03651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15902206-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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