Article
Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice.
Brain : a journal of neurology - 1 Aug 2005
Bannerman P G, Hahn A, Ramirez S, Morley M, Bönnemann C, Yu S, Zhang G-X, Rostami A, Pleasure D
Abstract excerpt
Using adult male C57BL/6 mice that express a yellow fluorescent protein transgene in their motor neurons, we induced experimental autoimmune encephalomyelitis (EAE) by immunization with myelin oligodendrocyte glycoprotein peptide 35-55 (MOG peptide) in complete Freund's adjuvant (CFA). Control mice of the same transgenic strain received CFA without MOG peptide. Early in the course of their illness, the EAE mice...
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