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Article

Mice devoid of Tau have increased susceptibility to neuronal damage in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Journal of neuropathology and experimental neurology - 1 May 2012

Weinger Jason G, Davies Peter, Acker Christopher M, Brosnan Celia F, Tsiperson Vladislav, Bayewitz Ashrei, Shafit-Zagardo Bridget

Abstract excerpt

The abundant axonal microtubule-associated protein tau regulates microtubule and actin dynamics, thereby contributing to normal neuronal function. We examined whether mice deficient in tau (Tau(-/-)) or with high levels of human tau differ from wild-type (WT) mice in their susceptibility to neuro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22487860
DOI: 10.1097/NEN.0b013e3182540d2e
PMCID: PMC3627392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22487860-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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