Article
The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure.
The Journal of clinical endocrinology and metabolism - 1 Nov 2017
Manosroi Worapaka, Tan Jia Wei, Rariy Chevon M, Sun Bei, Goodarzi Mark O, Saxena Aditi R, Williams Jonathan S, Pojoga Luminita H, Lasky-Su Jessica, Cui Jinrui, Guo Xiuqing, Taylor Kent D, Chen Yii-Der I, Xiang Anny H, Hsueh Willa A, Raffel Leslie J, Buchanan Thomas A, Rotter Jerome I, Williams Gordon H, Seely Ellen W
Abstract excerpt
Context: Hypertension in young women is uncommon compared with young men and older women. Estrogen appears to protect most women against hypertension, with incidence increasing after menopause. Because some premenopausal women develop hypertension, estrogen may play a different role in these women. Genetic variations in the estrogen receptor (ER) are associated with cardiovascular disease. ER-β, encoded by ESR2,...
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