Article
Monocyte- and endothelial-derived microparticles induce an inflammatory phenotype in human podocytes.
Nephron. Experimental nephrology - 1 Jan 2011
Eyre Jeanette, Burton James O, Saleem Moin A, Mathieson Peter W, Topham Peter S, Brunskill Nigel J
Abstract excerpt
BACKGROUND/AIMS: Proteinuria is associated with cardiovascular and chronic kidney disease. Microparticles (MPs) are bioactive vesicles shed from activated cells and also linked to cardiovascular disease. MP-like structures have been identified in the glomerular basement membrane, urinary space and between the glomerular basement membrane and the podocyte. We hypothesised that circulating MPs may provide a link...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
