Article
Sterol uptake in Candida glabrata: rescue of sterol auxotrophic strains.
Diagnostic microbiology and infectious disease - 1 Aug 2005
Bard Martin, Sturm Aaron M, Pierson Charles A, Brown Shaleak, Rogers Kristina M, Nabinger Sarah, Eckstein James, Barbuch Robert, Lees N D, Howell Susan A, Hazen Kevin C
Abstract excerpt
Candida glabrata is emerging as a more common and important human pathogen. It is less susceptible to azole antifungals than Candida albicans, thus, posing some unique treatment challenges. Previously undetected C. glabrata isolates were identified from clinical specimens by adding bile to the growth medium. Cholesterol was found to be the responsible ingredient in bile. Six bile-dependent isolates were...
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