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Article

The Candida glabrata Parent Strain Trap: How Phenotypic Diversity Affects Metabolic Fitness and Host Interactions.

Microbiology spectrum - 14 Feb 2023

Usher Jane, Ribeiro Gabriela F, Childers Delma S

Abstract excerpt

Reference strains improve reproducibility by standardizing observations and methodology, which has ultimately led to important insights into fungal pathogenesis. However, recent investigations have highlighted significant genotypic and phenotypic heterogeneity across isolates that influence genetic circuitry and virulence within a species. Candida glabrata is the second leading cause of candidiasis, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36633405
DOI: 10.1128/spectrum.03724-22
PMCID: PMC9927409

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