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Article

Galanin overexpressing transgenic mice.

Neuropeptides - 1 Jan 2000

Crawley Jacqueline N, Mufson Elliott J, Hohmann John G, Teklemichael Dawit, Steiner Robert A, Holmberg Kristina, Xu Zhi-Qing D, Blakeman Karin Hygge, Xu Xiao-Jun, Wiesenfeld-Hallin Zsuzsanna, Bartfai Tamas, Hökfelt Tomas

Abstract excerpt

Galanin overexpressing transgenic mice (GAL-tg) were generated on two different promoters. Both lines of GAL-tg displayed high levels of galanin in the hippocampus and reduced sensitivity to seizures, as compared to their respective wildtype littermate controls (WT). Performance deficits on learning and memory tasks, impaired long-term potentiation, reduced hippocampal excitability, lower evoked glutamate...

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Source

Identifiers

PMID: 12359505
DOI: 10.1054/npep.2002.0891

Genes

GAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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