Article
Demographic and genetic characteristics of patients with borderline ovarian tumors as compared to early stage invasive ovarian cancer.
Gynecologic oncology - 1 Jun 2005
Gotlieb Walter H, Chetrit Angela, Menczer Joseph, Hirsh-Yechezkel Galit, Lubin Flora, Friedman Eitan, Modan Baruch, Ben-Baruch Gilad
Abstract excerpt
OBJECTIVE: Evaluation whether Jewish founder mutations in BRCA predispose to borderline tumors as they do to early invasive ovarian cancers. METHODS: All Jewish women with borderline or invasive ovarian tumors, diagnosed over a 5-year period (1994-1999), were identified in the frame of a nationwide epidemiological study on ovarian cancer in Israel. Out of a total of 1489 patients, 1269 were interviewed; of them...
Topics
- Adult
- Age Factors
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Humans
- Israel
- Jews
- Middle Aged
- Neoplasm Invasiveness
- Neoplasm Staging
- Ovarian Neoplasms
