Article
BRCA mutations and outcome in epithelial ovarian cancer (EOC): experience in ethnically diverse groups.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2013
Safra T, Lai W C, Borgato L, Nicoletto M O, Berman T, Reich E, Alvear M, Haviv I, Muggia F M
Abstract excerpt
BACKGROUND: Epithelial ovarian cancer (EOC) patients with BRCA mutations have better prognosis than nonhereditary cases matched for histology and stage and age at diagnosis, especially Ashkenazi Jews (AJ). MATERIALS AND METHODS: We retrospectively reviewed data on 700 highly ethnically heterogeneous patients diagnosed with stage Ic-IV EOC and evaluated for BRCA status between 1995 and 2009 in American, Israeli,...
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