Article
A population-based study of BRCA1 and BRCA2 mutations in Jewish women with epithelial ovarian cancer.
Obstetrics and gynecology - 1 Jan 1999
Lu K H, Cramer D W, Muto M G, Li E Y, Niloff J, Mok S C
Abstract excerpt
OBJECTIVE: To determine the frequency of BRCA1 mutations 185delAG and 5382insC and BRCA2 mutation 6174delT in Jewish women with ovarian cancer and in matched controls in a population-based study. METHODS: Forty-eight Jewish women with epithelial ovarian cancer (32 invasive and 16 borderline) and...
Topics
- BRCA2 Protein
- DNA Mutational Analysis
- Female
- Genes, BRCA1
- Humans
- Jews
- Middle Aged
- Mutation
- Neoplasm Proteins
- Ovarian Neoplasms
- Transcription Factors
