Article
Quantification of G protein Gaalphas subunit splice variants in different human tissues and cells using pyrosequencing.
Gene expression - 1 Jan 2005
Frey Ulrich H, Nückel Holger, Dobrev Dobromir, Manthey Iris, Sandalcioglu I E, Eisenhardt Andreas, Worm Karl, Hauner Hans, Siffert Winfried
Abstract excerpt
The G protein Galphas is derived from four alternatively spliced transcripts, two long variants (Galphas(L)+CAG and Galphas(L)-CAG), which include an extra 45-bp segment, and two short variants (Galphas(S)+CAG and Galphas(S)-CAG). The long and short forms differ in each case by splicing in or out of a serine residue encoded at the 3' end of the variable exon 3. The relative expression of all four variants in...
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