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Article

Papillomavirus capsid mutation to escape dendritic cell-dependent innate immunity in cervical cancer.

Journal of virology - 1 Jun 2005

Yang Rongcun, Wheeler Cosette M, Chen Xiaojiang, Uematsu Satoshi, Takeda Kiyoshi, Akira Shizuo, Pastrana Diana V, Viscidi Raphael P, Roden Richard B S

Abstract excerpt

Infection with oncogenic human papillomaviruses (HPVs), typified by HPV type 16 (HPV16), is a necessary cause of cervical cancer. Prophylactic vaccination with HPV16 L1 virus-like particles (VLPs) provides immunity. HPV16 VLPs activate dendritic cells and a potent neutralizing immunoglobulin G (IgG) response, yet many cervical cancer patients fail to generate detectable VLP-specific IgG. Therefore, we examined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15890912
DOI: 10.1128/JVI.79.11.6741-6750.2005
PMCID: PMC1112150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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