Article
Susceptibility of naturally human papillomavirus type 16 major capsid protein L1 variants to vaccines and predictions of future evolutionary trends.
Tumour virus research - 1 Jun 2026
Yu Dongbo, Wang Jiao, Li Ying, Wang Hui, Zhang Jieqiong, Wang Mingming, Li Haotian, Zhang Li, Zhu Na, Lu Xuexin, Wang Shiwen
Abstract excerpt
Human papillomavirus type 16 (HPV16) causes over 50% of HPV-related cervical cancers. With the widespread use of virus-like particle (VLP)-based HPV prophylactic vaccines, investigating the differences in viral assembly, infectivity and antigenic properties among different variants is highly important for further eliminating diseases caused by HPV. We analyzed HPV16 L1 protein sequences from the NCBI database and...
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