Article
HPV16 L1 diversity and its potential impact on the vaccination-induced immunity.
Gene - 15 Jul 2020
El Aliani Aissam, El Abid Hassan, Kassal Yassmine, Khyatti Meriem, Attaleb Mohammed, Ennaji Moulay Mustapha, El Mzibri Mohamed
Abstract excerpt
Human Papillomavirus 16 (HPV16) is the most oncogenic HPV and the most associated genotype with cervical cancer development and progression. Currently, all developed vaccines are targeting HPV16 and were designed based on the major L1 capsid protein. Thus, evaluation of the diversity of HPV16 L1 sequence, mainly in the antigenic regions, will be of a great interest to assess the efficacy of the prophylactic...
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