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Article

Study of infectious virus production from HPV18/16 capsid chimeras.

Virology - 30 Sept 2010

Chen Horng-Shen, Bromberg-White Jennifer, Conway Michael J, Alam Samina, Meyers Craig

Abstract excerpt

Using the HPV18 genome as the backbone, we exchanged the HPV18 L2 or L1 genes with those of HPV16. The intertypical exchange of HPV18 L1 with the HPV16 L1 produced genomes that efficiently replicated and produced infectious virus. Genomes containing an intertypical exchange of HPV18 L2 for the HPV16 L2 failed to produce infectious virus in multiple independently derived cell lines. Using chimeric constructs of...

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Identifiers

PMID: 20598725
DOI: 10.1016/j.virol.2010.05.019
PMCID: PMC2923236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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