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Article

Five novel elements involved in the regulation of mitosis in fission yeast.

Molecular & general genetics : MGG - 1 Apr 1992

Warbrick E, Fantes P A

Abstract excerpt

Five new elements of the mitotic control in the fission yeast Schizosaccharomyces pombe were isolated from gene libraries as multicopy suppressors of the conditional lethal phenotype of win1-1 wee1ts cdc25ts triple mutant strains. These genes were designated wis1(+)-wis5+ for win suppressing, and...

Topics

Cell Cycle
Cloning, Molecular
Gene Library
Genes, Fungal
Genes, Lethal
Genes, Suppressor
Genetic Complementation Test
Genetic Vectors
Mitosis
Mutagenesis, Insertional
Phenotype
Plasmids
Restriction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizosaccharomyces

Source

Identifiers

PMID: 1588914
DOI: 10.1007/BF00266249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1588914-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Five novel elements involved in the regulation of mitosis in fission yeast.PMID 1588914Read ↗

The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity.Semantic proximity Read ↗

stf1: non-wee mutations epistatic to cdc25 in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

spo12 is a multicopy suppressor of mcs3 that is periodically expressed in fission yeast mitosis.Semantic proximity Read ↗

Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.Semantic proximity Read ↗

The Win1 mitotic regulator is a component of the fission yeast stress-activated Sty1 MAPK pathway.Semantic proximity Read ↗

stf1: a new suppressor of the mitotic control gene, cdc25, in Schizosaccharomyces pombe.Semantic proximity Read ↗

Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication.Semantic proximity Read ↗

Novel alleles of cdc13 and cdc2 isolated as suppressors of mitotic catastrophe in Schizosaccharomyces pombe.Semantic proximity Read ↗

mik1(+) G1-S transcription regulates mitotic entry in fission yeast.Semantic proximity Read ↗

Hyperthermotolerant fission yeast mutations, sow1 and sow2, suppress the cell cycle defect and stress sensitivity of MAP kinase kinase wis1Delta.Semantic proximity Read ↗

Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.Semantic proximity Read ↗

Coordination of initiation of nuclear division and initiation of cell division in Schizosaccharomyces pombe: genetic interactions of mutations.Semantic proximity Read ↗

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