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Article

Glutathione S-transferase P1 and lung function in patients with alpha1-antitrypsin deficiency and COPD.

Chest - 1 May 2005

Rodriguez Francisco, de la Roza Cristian, Jardi Rosendo, Schaper Melanie, Vidal Rafael, Miravitlles Marc

Abstract excerpt

BACKGROUND: The glutathione S-transferase P1 (GSTP1) gene is involved in detoxification of electrophilic substances of tobacco smoke. A polymorphism at nucleotide 315 of this gene alters its enzymatic activity. OBJECTIVE: We analyzed the association between the variability in the GSTP1 gene and impairment in lung function in smokers with and without alpha(1)-antitrypsin (AAT) deficiency and COPD. POPULATION AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15888825
DOI: 10.1378/chest.127.5.1537

Genes

GSTP1
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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