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MDR1 gene polymorphism in allogeenic kidney transplant patients with tremor.

Pharmacological reports : PR - 1 Jan 2000

Kotrych Katarzyna, Domański Leszek, Górnik Wanda, Droździk Marek

Abstract excerpt

P-glycoprotein (P-gp), an ATP-dependent efflux pump, is a membrane protein encoded by MDR1 gene, which demonstrates functional polymorphism. It is present in endothelial cells of the blood-brain barrier. P-gp pays a role in transmembrane transport of various xenobiotics, thus limiting their accumulation in the central nervous system. Cyclosporine A which is used as an immunosuppressive drug in patients with...

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PMID: 15886424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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