Article
The genetics of susceptibility to cutaneous melanoma.
Drugs of today (Barcelona, Spain : 1998) - 1 Mar 2005
Newton Bishop Julia A, Bishop D Timothy
Abstract excerpt
The most common genetic determinants of skin cancer are the genes that control skin color so that the genes expressed as black skin are protective. Within the white population variants at the MC1R locus are shown to increase susceptibility, and recent evidence suggests that polymorphisms in the OCA2 gene interact to modify risk. Other as-yet-unidentified pigment genes may also play a role in susceptibility to...
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