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Article

Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic<i>HOXB4</i>expression

9 May 2005

Abstract excerpt

Despite the need for alternative sources of human hematopoietic stem cells (HSCs), the functional capacity of hematopoietic cells generated from human embryonic stem cells (hESCs) has yet to be evaluated and compared with adult sources. Here, we report that somatic and hESC-derived hematopoietic cells have similar phenotype and in vitro clonogenic progenitor activity. However, in contrast with somatic cells,...

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PMID: 15883170
DOI: 10.1084/jem.20041888

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