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Article

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

21 Nov 2012

Abstract excerpt

UNLABELLED: Several studies have demonstrated that hematopoietic cells originate from endotheliumin early development; however, the phenotypic progression of progenitor cells during human embryonic hemogenesis is not well described. Here, we define the developmental hierarchy among intermediate populations of hematopoietic progenitor cells (HPCs) derived from human embryonic stem cells (hESCs). We genetically...

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PMID: 23169780
DOI: 10.1182/blood-2012-07-444208

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