Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

7 Nov 2014

Abstract excerpt

Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells. This could be due to short half-life of hematopoietic stem cells in culture or, alternatively, human embryonic stem cell-initiated hematopoiesis may be hematopoietic stem cell-independent,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Immune Cell Function and Interaction
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25381126
DOI: 10.3324/haematol.2014.112144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesisPMID 25381126Read ↗

Emergence of CD43-Expressing Hematopoietic Progenitors from Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Characterization of hematopoietic progenitors from human yolk sacs and embryosSemantic proximity Read ↗

MYB bi-allelic targeting abrogates primitive clonogenic progenitors while the emergence of primitive blood cells is not affectedSemantic proximity Read ↗

Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures.Semantic proximity Read ↗

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesisSemantic proximity Read ↗

A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specificationSemantic proximity Read ↗

Phenotypic and functional characterization of hematopoietic stem cells.Semantic proximity Read ↗

Embryonic hematopoiesis.Semantic proximity Read ↗

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.Semantic proximity Read ↗

Definitive-like erythroid cells derived from human embryonic stem cells coexpress high levels of embryonic and fetal globins with little or no adult globinSemantic proximity Read ↗

Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis.Semantic proximity Read ↗

CD32 allows capturing blood cells emergence in slow motion during human embryonic developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.