G2m(23) immunoglobulin allotype and immunity to Haemophilus influenzae type b.

doi:10.1093/infdis/165-supplement_1-s66

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Article

G2m(23) immunoglobulin allotype and immunity to Haemophilus influenzae type b.

The Journal of infectious diseases - 1 Jun 1992

Granoff D M, Holmes S J

Abstract excerpt

G2m(23), an allotype on IgG2 molecules, is detected in sera of about two of three Caucasians. Adults who are homozygous for G2m(23) have IgG2 antibody responses to types 14 and 18C pneumococcal polysaccharides fourfold higher than those of homozygous-negative subjects. Adults homozygous for G2m(2...

Topics

Bacterial Capsules
Bacterial Vaccines
Genes, Immunoglobulin
Genetic Predisposition to Disease
Haemophilus Infections
Haemophilus Vaccines
Haemophilus influenzae
Heterozygote
Homozygote
Humans
Immunoglobulin G
Immunoglobulin Gm Allotypes
Polysaccharides, Bacterial
Vaccination

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