Article
Three new alleles of IGHG2 and their prevalence in Danish Caucasians, Mozambican Blacks and Japanese.
Tissue antigens - 1 Mar 2003
Hougs L, Garred P, Kawasaki T, Kawasaki N, Svejgaard A, Barington T
Abstract excerpt
The human IGHG2 gene locus is polymorphic, encoding two known allotypes of IgG2: G2m(n-) and G2m(n+). The allele prevalence varies greatly between different ethnic groups and individual genotypes correlate with the level of plasma IgG2 and with antibody responses to certain polysaccharide antigens. In this study, we present three new alleles of IGHG2 (IGHG2*03, 04, and 05), and a complete sequence specific PCR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
