Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haptoglobin polymorphism and the immune response after hepatitis B vaccination.

Vaccine - 1 Sept 1993

Louagie H, Delanghe J, Desombere I, De Buyzere M, Hauser P, Leroux-Roels G

Abstract excerpt

One hundred healthy Caucasian medical students (age 22 +/- 1 years) were vaccinated with a recombinant hepatitis B vaccine and their haptoglobin types were determined. A relationship between haptoglobin type and immune response to the vaccine was observed. Subjects with a 2-2 haptoglobin phenotype produced significantly lower hepatitis B antibody titres than those having a 1-1 or 2-1 haptoglobin phenotype. The...

Topics

Adult
Antibody Formation
Electrophoresis, Starch Gel
Female
Haptoglobins
Hepatitis B Antibodies
Hepatitis B Surface Antigens
Hepatitis B Vaccines
Humans
Kinetics
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymorphism, Genetic

Vaccination

Source

Identifiers

PMID: 8256500
DOI: 10.1016/0264-410x(93)90041-u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8256500-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Haptoglobin polymorphism and the immune response after hepatitis B vaccination.PMID 8256500Read ↗

Haptoglobin polymorphism and chronic hepatitis C.Semantic proximity Read ↗

Association of HLA phenotype with primary non-response to recombinant hepatitis B vaccine: a study from north India.Semantic proximity Read ↗

Haptoglobin phenotype and epithelial ovarian cancer.Semantic proximity Read ↗

TH1 and TH2 responses are influenced by HLA antigens in healthy neonates vaccinated with recombinant hepatitis B vaccine.Semantic proximity Read ↗

Hepatitis B third-generation vaccines: improved response and conventional vaccine non-response--evidence for genetic basis in humans.Semantic proximity Read ↗

Relationship between the reactivity to hepatitis B virus vaccination and the frequency of MHC class I, II and III alleles in haemodialysis patients.Semantic proximity Read ↗

G2m(23) immunoglobulin allotype and immunity to Haemophilus influenzae type b.Semantic proximity Read ↗

Human leukocyte antigens influence the immune response to a pre-S/S hepatitis B vaccine.Semantic proximity Read ↗

The importance of A3 allele in response to hepatitis B vaccine in end-stage renal disease patients.Semantic proximity Read ↗

HLA genetic heterogeneity of hepatitis B vaccine response in hemodialyzed patients.Semantic proximity Read ↗

The immune response to hepatitis B vaccine in humans: inheritance patterns in families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.