Article
Haptoglobin polymorphism and the immune response after hepatitis B vaccination.
Vaccine - 1 Sept 1993
Louagie H, Delanghe J, Desombere I, De Buyzere M, Hauser P, Leroux-Roels G
Abstract excerpt
One hundred healthy Caucasian medical students (age 22 +/- 1 years) were vaccinated with a recombinant hepatitis B vaccine and their haptoglobin types were determined. A relationship between haptoglobin type and immune response to the vaccine was observed. Subjects with a 2-2 haptoglobin phenotype produced significantly lower hepatitis B antibody titres than those having a 1-1 or 2-1 haptoglobin phenotype. The...
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