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Article

Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2006

Jönsson Göran, Oxelius Vivi-Anne, Truedsson Lennart, Braconier Jean Henrik, Sturfelt Gunnar, Sjöholm Anders G

Abstract excerpt

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish patients with C2D...

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Source

Identifiers

PMID: 16785571
DOI: 10.4049/jimmunol.177.1.722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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