Article
Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation.
Molecular and cellular biochemistry - 1 Mar 2005
Choi So-Jung, Moon Jae-Hoon, Ahn Young-Wook, Ahn Jin-Hyun, Kim Dong-Uk, Han Tae-Hee
Abstract excerpt
Tsc-22 was isolated as a TGF-beta-inducible gene by differential screening of the mouse osteoblastic cell cDNA library [J Biol Chem 267 (1992) 10219]. tsc-22 mRNA is expressed in almost all organs of mice and humans and its expression is induced in a variety of cell lines by many different factors including TGF-beta, phorbol ester, serum, and progestin. tsc-22 encodes a 18-kd protein that contains a leucine...
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