Article
Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor β signaling
19 Jan 2004
Abstract excerpt
BACKGROUND: Transforming growth factor-betas (TGF-betas), bone morphogenetic proteins (BMPs) and activins are important regulators of developmental cell growth and differentiation. Signaling by these factors is mediated chiefly by the Smad family of latent transcription factors. RESULTS: There are a large number of uncharacterized cDNA clones that code for novel proteins with homology to known signaling...
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