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Article

The VEGF +405 CC promoter polymorphism is associated with an impaired prognosis in patients with chronic heart failure: a MERIT-HF substudy.

Journal of cardiac failure - 1 May 2005

van der Meer Peter, De Boer Rudolf A, White Hazel L, van der Steege Gerrit, Hall Alistair S, Voors Adriaan A, van Veldhuisen Dirk J

Abstract excerpt

BACKGROUND: A common polymorphism positioned at +405 of the vascular endothelial growth factor (VEGF) gene is known to influence VEGF protein production. In contrast, a second polymorphism, positioned at -460 polymorphism, has no reported functional effects. VEGF is linked to angiogenesis and might directly influence the clinical outcome of patients with chronic heart failure (CHF). We investigated the...

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Identifiers

PMID: 15880336
DOI: 10.1016/j.cardfail.2004.11.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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