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Article

Single-nucleotide polymorphisms of VEGF gene are associated with risk of congenital valvuloseptal heart defects.

American heart journal - 1 Apr 2006

Vannay Adám, Vásárhelyi Barna, Környei Mária, Treszl András, Kozma Gergely, Györffy Balázs, Tulassay Tivadar, Sulyok Endre

Abstract excerpt

BACKGROUND: Disturbed vascular endothelial growth factor (VEGF) production during early heart morphogenesis causes endocardial cushion malformation, which results in congenital heart disease (CHD). We tested whether functional VEGF -460T/C and +405G/C polymorphisms that have an impact on VEGF levels were associated with CHD. METHODS: Dried blood samples were collected from 102 CHD children and 112 healthy control...

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Identifiers

PMID: 16569553
DOI: 10.1016/j.ahj.2005.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Single-nucleotide polymorphisms of VEGF gene are associated with risk of congenital valvuloseptal heart defects.PMID 16569553Read ↗

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