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The +405 GG variant of vascular endothelial growth factor polymorphism is associated with poor prognosis in patients undergoing coronary artery bypass graft surgery.

Polskie Archiwum Medycyny Wewnetrznej - 1 Nov 2009

Pastuszczak Maciej, Branicka Agnieszka, Jakiela Bogdan, Stepień Ewa, Jaworek Andrzej K, Wojas-Pelc Anna, Kapelak Bogusław, Sadowski Jerzy

Abstract excerpt

INTRODUCTION: Coronary artery bypass graft (CABG) surgery is associated with systemic response and increased concentrations of numerous cytokines. Vascular endothelial growth factor (VEGF) related pathway also seems to be involved in inflammatory response induced by CABG. OBJECTIVES: The aim of this study was to analyze the association between the VEGF gene +405 G>C polymorphism (linked to serum VEGF production),...

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PMID: 19920796

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