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Article

Epistasis and the adaptability of an RNA virus.

Genetics - 1 Jul 2005

Sanjuán Rafael, Cuevas José M, Moya Andrés, Elena Santiago F

Abstract excerpt

We have explored the patterns of fitness recovery in the vesicular stomatitis RNA virus. We show that, in our experimental setting, reversions to the wild-type genotype were rare and fitness recovery was at least partially driven by compensatory mutations. We compared compensatory adaptation for genotypes carrying (1) mutations with varying deleterious fitness effects, (2) one or two deleterious mutations, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Sequence Analysis, DNA

Share to Vesicular stomatitis Indiana virus

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Source

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Identifiers

PMID: 15879507
DOI: 10.1534/genetics.105.040741
PMCID: PMC1451175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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