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Article

Coding block and 5 leader cistron polymorphisms of the beta2-adrenergic receptor.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1999

McGraw D W, Liggett S B

Abstract excerpt

The gene encoding the beta2-adrenergic receptor (beta2AR) is highly polymorphic in the human population. Common polymorphisms in the receptor coding block (amino acids 16 and 27) affect agonist-promoted downregulation. Another common polymorphism in the 5' leader cistron of the beta2AR gene also regulates receptor expression, but does so through a mechanism that is independent of agonist exposure. None of these...

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PMID: 10641566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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