Article
Cloning and functional characterization of dog transient receptor potential vanilloid receptor-1 (TRPV1).
European journal of pharmacology - 18 Apr 2005
Phelps P Tara, Anthes John C, Correll Craig C
Abstract excerpt
Transient receptor potential vanilloid receptor-1 (TRPV1) is a sensory neuron-specific cation channel capable of integrating various noxious chemical and physical stimuli. The dog orthologue of TRPV1 was cloned using cDNA from nodose ganglia and heterologously expressed in HEK293(OFF) cells. At the amino acid level, dTRPV1 displays 85-89% sequence identity to other TRPV1 orthologues. Molecular pharmacological...
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