Alterations in the superoxide dismutase gene of an isoniazid-resistant strain of Mycobacterium tuberculosis.

doi:10.1128/iai.60.6.2160-2165.1992

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Article

Alterations in the superoxide dismutase gene of an isoniazid-resistant strain of Mycobacterium tuberculosis.

Infection and immunity - 1 Jun 1992

Zhang Y, Garcia M J, Lathigra R, Allen B, Moreno C, van Embden J D, Young D

Abstract excerpt

Genetic analysis of a set of six Mycobacterium tuberculosis strains differing in virulence for the guinea pig revealed an altered restriction enzyme fragmentation pattern associated with the superoxide dismutase (SOD) gene in a low-virulence, isoniazid-resistant strain. In addition, it was found...

Topics

Animals
Base Sequence
Drug Resistance, Microbial
Genes, Bacterial
Guinea Pigs
Isoniazid
Molecular Sequence Data
Mutation
Mycobacterium tuberculosis
Superoxide Dismutase

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