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Article

Activation of Lyt-2 associated with distant upstream insertion of an SL3-3 provirus.

Immunogenetics - 1 Jan 1992

Anson D S, Clarkin K, Hyman R

Abstract excerpt

Two Lyt-2+ mutants of the T-cell lymphoma SL12.4.10 were selected by fluorescence activated cell sorting. Both mutants expressed Lyt-2 (CD8 alpha-chain) but not Lyt-3 (CD8 beta-chain). Derivatives of one Lyt-2+ mutant that expressed Lyt-3 could be isolated by sorting for Lyt-3+ cells. Southern blotting analysis indicated that both mutants had structural rearrangements within or immediately 3' of the Lyt-3 gene,...

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Identifiers

PMID: 1587551
DOI: 10.1007/BF00209286

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