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Article

Fumaric acid overproduction in yeast mutants deficient in fumarase.

FEMS microbiology letters - 1 Mar 1992

Kaclíková E, Lachowicz T M, Gbelská Y, Subík J

Abstract excerpt

A nuclear mutant of Saccharomyces cerevisiae deficient in mitochondrial fumarase has been identified through the in vitro biochemical assay of enzyme activity after visual selection due to an increased acidification ability of its colonies. Cells of the fumarase-deficient mutant fermenting glucos...

Topics

Anaerobiosis
Antifungal Agents
Chromatography, High Pressure Liquid
Fatty Acids, Unsaturated
Fumarate Hydratase
Fumarates
Hydrogen-Ion Concentration
Kinetics
Methacrylates
Mutation
Oxygen Consumption
Saccharomyces cerevisiae

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Identifiers

PMID: 1587456
DOI: 10.1016/0378-1097(92)90667-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1587456-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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