Involvement of mitochondrial aldehyde dehydrogenase ALD5 in maintenance of the mitochondrial electron transport chain in Saccharomyces cerevisiae.

doi:10.1111/j.1574-6968.1999.tb08856.x

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Article

Involvement of mitochondrial aldehyde dehydrogenase ALD5 in maintenance of the mitochondrial electron transport chain in Saccharomyces cerevisiae.

FEMS microbiology letters - 15 Dec 1999

Kurita O, Nishida Y

Abstract excerpt

The physiological role of mitochondrial aldehyde dehydrogenase (ALD5) was investigated by analysis of the ald5 mutant (AKD321) in Saccharomyces cerevisiae. K(+)-activated ALDH activity of the ald5 mutant was about 80% of the wild-type in the mitochondrial fraction, while the respiratory activity of the ald5 mutant was greatly reduced. Cytochrome content was also reduced in the ald5 mutant. Enzymatic analysis...

Topics

Aldehyde Dehydrogenase
Cytochromes
Ethanol
Gene Deletion
Glucose
Mitochondria
Mutation
Oxidative Phosphorylation
Potassium
Promoter Regions, Genetic
Saccharomyces cerevisiae
Spectrophotometry
Time Factors

Source

Open in PubMed

Identifiers

PMID: 10585550
DOI: 10.1111/j.1574-6968.1999.tb08856.x

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