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Article

Isolation of peroxisome assembly mutants from Saccharomyces cerevisiae with different morphologies using a novel positive selection procedure.

The Journal of cell biology - 1 Oct 1992

Van der Leij I, Van den Berg M, Boot R, Franse M, Distel B, Tabak H F

Abstract excerpt

We have developed a positive selection system for the isolation of Saccharomyces cerevisiae mutants with disturbed peroxisomal functions. The selection is based on the lethality of hydrogen peroxide (H2O2) that is produced in wild type cells during the peroxisomal beta-oxidation of fatty acids. In total, 17 mutants having a general impairment of peroxisome biogenesis were isolated, as revealed by their inability...

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Identifiers

PMID: 1356111
DOI: 10.1083/jcb.119.1.153
PMCID: PMC2289622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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