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Article

A novel role for the mitotic spindle during DNA segregation in yeast: promoting 2 microm plasmid-cohesin association.

Molecular and cellular biology - 1 May 2005

Mehta Shwetal, Yang Xian-Mei, Jayaram Makkuni, Velmurugan Soundarapandian

Abstract excerpt

The 2 microm circle plasmid in Saccharomyces cerevisiae is a model for a stable, high-copy-number, extrachromosomal "selfish" DNA element. By combining a partitioning system and an amplification system, the plasmid ensures its stable propagation and copy number maintenance, even though it does not provide any selective advantage to its host. Recent evidence suggests that the partitioning system couples plasmid...

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Identifiers

PMID: 15870297
DOI: 10.1128/MCB.25.10.4283-4298.2005
PMCID: PMC1087726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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