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Evolutionary cell biology of chromosome segregation: insights from trypanosomes

1 May 2013

Abstract excerpt

Faithful transmission of genetic material is essential for the survival of all organisms. Eukaryotic chromosome segregation is driven by the kinetochore that assembles onto centromeric DNA to capture spindle microtubules and govern the movement of chromosomes. Its molecular mechanism has been actively studied in conventional model eukaryotes, such as yeasts, worms, flies and human. However, these organisms are...

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PMID: 23635522
DOI: 10.1098/rsob.130023

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