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Article

The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks.

Molecular and cellular biology - 1 May 2005

Shim Eun Yong, Ma Jia-Lin, Oum Ji-Hyun, Yanez Yvonne, Lee Sang Eun

Abstract excerpt

Repair of chromosome double-strand breaks (DSBs) is central to cell survival and genome integrity. Nonhomologous end joining (NHEJ) is the major cellular repair pathway that eliminates chromosome DSBs. Here we report our genetic screen that identified Rsc8 and Rsc30, subunits of the Saccharomyces cerevisiae chromatin remodeling complex RSC, as novel NHEJ factors. Deletion of RSC30 gene or the C-terminal...

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Identifiers

PMID: 15870268
DOI: 10.1128/MCB.25.10.3934-3944.2005
PMCID: PMC1087737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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