Article
Genome-wide linkage scan for submaximal exercise heart rate in the HERITAGE family study.
American journal of physiology. Heart and circulatory physiology - 1 Dec 2007
Spielmann Nadine, Leon Arthur S, Rao D C, Rice Treva, Skinner James S, Rankinen Tuomo, Bouchard Claude
Abstract excerpt
The purpose of this study was to identify regions of the human genome linked to submaximal exercise heart rates in the sedentary state and in response to a standardized 20-wk endurance training program in blacks and whites of the HERITAGE Family Study. A total of 701 polymorphic markers covering the 22 autosomes were used in the genome-wide linkage scan, with 328 sibling pairs from 99 white nuclear families and...
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