Article
Association analysis of -416 G>C polymorphism of T-cell immunoglobulin and mucin domain-1 gene with asthma in Iran.
International journal of immunogenetics - 1 Aug 2015
Shirzade H, Meshkat R, Ganjalikhani-Hakemi M, Mosayebian A, Ghasemi R, Deress F, Parchami Barjui S, Sadri M, Salehi R
Abstract excerpt
TIM (T-cell immunoglobulin (Ig) and mucin domain)-1, one of the members of TIM family, expresses on Th2 cells and promotes the production of Th2 signature cytokines. This can increase a series of responses in these cells which could be one of the causes of asthma or asthma-related phenotypes. The aim of this study was to investigate whether a TIM-1 promoter single nucleotide polymorphism (SNP), -416 G>C, is...
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